In the past, advanced macrolide monotherapy (azithromycin and clarithromycin) was recommended for outpatient treatment of CAP and COPD AE with acute bronchitis. I'm starting to question if this is consistent with best practice.

Listen as we critically appraise the MACMAN Trial (JAMA 2017;317(5):483-493. doi:10.1001/jama.2016.20603).

This trial is an RCT looking at VL vs DL for routine orotracheal intubation in the intensive care unit.

This is part of our Journal Club Series - if you haven't listened to episode 1, hit pause and go listen to that first!